1. Always do your homework
Get travel books and/or look up your location on the internet before you go so you get an idea of popular sights to see.
2. Bring the right equipment.
I use a general zoom lens (28-300mm) as a travel lens and supplement this with a wide-angle lens (10-24mm)
If necessary bring a small compact camera for photographing in the street where you may feel vulnerable with a large DSLR camera.
If you want to shoot in low light conditions, consider a more powerful flash gun.
3. Ask around when you arrive.
Locals like hotel staff, taxi drivers, and cafe staff will be glad to tell you of some spots that the locals go which most tourists are not aware of.
4. Be aware of time and light.
Check for sunrise and sunset times and also local weather forecasts via the internet.
5. Be flexible.
If you find a great spot be prepared to stay there longer than intended. Also, be prepared for the unexpected.
HAPPY SHOOTING !